Abstract:
A gene co-expression analysis on Lung adenocarcinoma data was done to find modules of genes that might highly impact the growth of this type of tumor. Along with that, cancer survival data was used to relate modules to prognostic significance for survival time. Analysis on microarray data revealed modules that were significant in gene enrichment analysis and 4 genes - TTk, C6orf173, CENPE, DCC1 were found that were significant in terms of survival time. A second analysis was done on a second set of RNAseq data and the significant genes in modules was found there, were also found in the RNAseq data implying that these genes might indeed play a crucial role in Lung adenocarcinoma.